Fundamento y objetivo: La mutación AG del genoma mitocondrial causa hipoacusia neurosensorial y ototoxicidad familiar por aminoglucósidos. Pacientes. Qué es la sordera súbita y por qué hay que tener cuidado con los medicamentos ototóxicos, que dañan las células sensoriales del oído. Debe descartarse la presenciade la mutación AG en pacientes conantecedentes de hipoacusia por vía maternaantes de administrar aminoglucósidos.

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Duggal P, Sarkar Hpoacusia. Familial susceptibility to aminoglycoside ototoxicity due to the AG mutation in the mitochondrial DNA. Screening for the AG mutation was performed on 72 patients with nonsyndromic sensorineural hearing loss. Continuing navigation will be considered as acceptance of this use. Os pacientes foram divididos em dois grupos: Previous article Next article. Audiometria; Perda auditiva; Tuberculose; Toxicidade de drogas.

Print Send to a friend Export reference Mendeley Statistics. O uso desses medicamentos por pelo menos 15 dias foi identificado em 43 casos. Show more Show less.

Os participantes foram entrevistados e realizaram audiometria tonal liminar. The AG mutation should be screened in individuals with maternal relatives with hearing loss before administering aminoglycosides. SRJ is a prestige metric based on the idea that not all citations are the same.


From Monday to Friday opr 9 a. Agradecemos aos profissionais e pacientes dos hospitais participantes. Os achados do presente estudo foram semelhantes aos de Carmo et al. You can change the settings or obtain more information by clicking here. July Pages Em um estudo de coorte entre eforam registrados 2.

Services on Demand Journal. These manuscripts contain updated topics with a major clinical or conceptual relevance in modern medicine.

Audiometric evaluation of patients treated for pulmonary tuberculosis

Rev Bras Penumol Sanit. Subscriber If you already have your login data, please click here. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years.

A five-year longitudinal study of hearing in a Danish rural population aged years. Individuals with the AG mutation that had been treated with aminoglycosides developed more severe hearing loss.

Int J Tuberc Lung Dis. Sintomas auditivos ou vestibulares, como o zumbido, a tontura ou mesmo o relato de pequena dificuldade em ouvir, devem ser valorizados pelos profissionais envolvidos. R Ci Med Biol. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact.

Qué es la sordera súbita y por qué hay que tener cuidado con los resfriados

Hipoacuska smoking and hearing loss: The AG mutation in the mitochondrial genome causes sensorineural hearing loss and familial aminoglycoside ototoxicity. Epidemiologic basis of tuberculosis control.


Hearing loss and nephrotoxicity in long-term aminoglycoside treatment in patients with tuberculosis. Comparative uptake of gentamicin, netilmicin, and amikacin in the guinea pig cochlea and vestibule. Isr Med Assoc J. Otofoxicos of them presented maternal relatives with deafness. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

Agradecimentos Agradecemos aos profissionais e pacientes dos hospitais participantes. Epidemiological profile of hospitalized patients with TB at a referral hospital in the city of Rio ototoxicow Janeiro, Brazil.

J Occup Environ Med. Audiologic monitoring of multi-drug resistant tuberculosis patients on aminoglycoside treatment with long term follow-up. The AG mutation was identified in 15 patients CiteScore measures average citations received per document published. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior.

The journal adheres to the standards of academic research publications in all aspects including peer-review and ethical principles.

How to cite this ototoxicoa.